Mitosol

Mitosol

Nutritional supplement for immune and metabolism support

Manganese Gluconate

Manganese is essential to all forms of life. Manganese plays an essential role in many cellular processes,

including lipid, protein, and carbohydrate metabolism, and is used by a diverse array of enzymes 1 .

Pangamic acid

Also known as B15, it can be found in rice bran, brewer’s yeast, barley, wheat seeds, oats, and core. To

be the gluconic acid ester of dimethylglycine, the latter compound being an intermediate in the choline

cycle, a metabolic cycle involved in energy transformation. It is capable of donating methyl groups in

certain metabolic synthetic processes occurring in the body 2 .

Betaine HCl

Betaine is found in microorganisms, plants, and animals and is a significant component of many foods,

including wheat, shellfish, spinach, and sugar beets.  It is rapidly absorbed and utilized as an osmolyte 3

and source of methyl groups, thereby helping maintain liver, heart, and kidney health. Betaine can

reduce the elevated serum homocysteine concentrations associated with mild or severe

hyperhomocystinuria via the methionine cycle and may play a role in epigenetics and athletic

performance 4 .

Sodium Diacetate

Sodium diacetate is sodium acetate with a slight flavor of acetic acid. It is used as a sour agent and pH

regulator. Its related metabolism of acetyl-coenzyme A (acetyl-CoA) confers numerous metabolic

functions, including energy production, lipid synthesis, and protein acetylation 5 .

SUGGESTED USE

Adults take 1- 3 capsules, 2-3 times daily before meals or as directed by a healthcare professional.

SIDE EFFECTS

No adverse side effects reported.

STORAGE

Store in a cool, dry place, away from direct light. Keep out of reach of children.

Reference

1. Andreini C, Bertini I, Cavallaro G, et al. Metal ions in biological catalysis: from enzyme databases

to general principles. JBIC Journal of Biological Inorganic Chemistry 2008;13:1205-1218.

2. Herbert V. Pangamic acid (" vitamin B-15"). American Journal of Clinical Nutrition (USA) 1979.

3. Kidd M, Ferket P, Garlich J. Nutritional and osmoregulatory functions of betaine. World's Poultry

Science Journal 1997;53:125-139.

4. Craig SA. Betaine in human nutrition. The American journal of clinical nutrition 2004;80:539-549.

5. Gao X, Lin S-H, Ren F, et al. Acetate functions as an epigenetic metabolite to promote lipid

synthesis under hypoxia. Nature communications 2016;7:11960.