Cortanin

Cortanin^TM

Support healthy heart

Improve cardiac function

Promote blood circulation

FUNCTIONS

Salvia Miltiorrhizaextract (Danshen) is a traditional Asian herbal medication used for its beneficial effects on the circulatory system. It has a long history in treating various markers of heart health including in the modern day where it has recently shown efficacy in cerebrovascular diseases and hyperlipidemia. [1] The extract of this plant has been shown to dilate coronary arteries, inhibit platelet aggregation,protect the myocardium from re-perfusion injury of the ischemic heart, and improve micro circulation. These beneficial functions are made possible by Danshensu or Salvianic Acid A an active ingredient of Salvia miltiorrhiza. It can activate the Nrf2 signaling pathway and boosts endogenous antioxidants to help scavenge free radicals and contribute to the recovery of cardiac function after I/R injury. [2] Another active ingredient Salvianolic acid B contributes to cardiac protection by inhibiting the oxidation of LDL proteins and inhibiting platelet aggregation.

Fibraurea Tinctoriaextract is a plant native to South East Asia and has been harvested from the wildas a source of medicine and dyestuff of Thailand and other Asian Countries. Theextract comes from the stems of this plant which contains many healthbeneficial alkaloids for instance columabamine, dehydrocorydalmine, and othersthat could be the biologically active components of this plant. [3] This plantexhibits a protective effect against myocardial infarction.

Magnesium (MgGluconate) is a very importantmineral for many systems in the body. This mineral is involved in over 300biochemical processes in the body including energy production, blood pressureregulation, muscle and nerve function. [4] More importantly, Magnesium islinked very closely to heart health as well as regulating normal bloodpressure. If the body’s magnesium levels are too low, arrhythmia can developwhich is a potentially fatal irregular heart rate. Fortunately, magnesium cancombat that risk by restoring healthy heart cell electrical functions, fightingarrhythmia at the source. Magnesium gluconate has been shown to have thehighest level of bioavailability out of all of the available magnesiumsupplements.

SUGGESTED USE 

Adults take 1-2 capsules.  Three timesdaily before meals or as directed by a healthcare professional. 

INGREDIENTS

Each capsule containing 500 mg of Proprietaryblend: Nano-curcumin, MSM, activated charcoal, bamboo salt, nano greens fromplants.  

SIDE EFFECTS 

No adverse side effects reported. 

STORAGE 

Store in a cool, dry place, away from directlight. Keep out of reach of children.

REFERENCES    

1. Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. (2005)
2. Yu J, et al. Danshensu protects isolated heart against ischemia reperfusion injury through activation of Akt/ERK1/2/Nrf2 signaling. Int J Clin Exp Med. 2015 Sep 15;8(9):14793-804.
3.   Itokawa,H., Mizuno, K., Tajima, R. and Takeya, K. 1986. Furanoditerpene glucosides fromFibraurea tinctoria. Phytochemistry, 25: 905-908
4.   Mordike,B. L., and Tü Ebert. "Magnesium:properties—applications—potential." Materials Science andEngineering: A 302.1 (2001): 37-45.